Non-pharmacological pain management strategies: a mini-review

Authors

  • Rafal Hussien Jawad
  • Qayssar Joudah Fadheel

DOI:

https://doi.org/10.60988/p.v37i2S.281

Keywords:

non-pharmacological intervention; transcutaneous electrical nerve stimulation; cognitive behavioural therapy; Quran therapy; strategies

Abstract

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Non-pharmacological interventions offer several advantages, including reduced medical costs, increased accessibility, broader applicability, ease of use, and greater patient satisfaction. These strategies may also reduce the patients’ pain levels while minimizing the adverse effects commonly associated with pharmacological treatments. However, non-pharmacological techniques have limitations concerning their applicability and efficacy. They are classified according to their mechanisms of action into four main categories: mind–body interventions, biological treatments, manipulative and body-based practices, and energy-based strategies. Common examples include the transcutaneous electrical nerve stimulation, heat therapy, massage therapy, light therapy, cognitive behavioural therapy, acupuncture, yoga, virtual reality therapy, Quran therapy, and aromatherapy. This mini-review provides an overview of the mechanisms through which these strategies alleviate pain, and highlights the advantages that contribute to their growing global appeal.

Author Biographies

Rafal Hussien Jawad

College of Pharmacy, University of Babylon, Hillah, Iraq

Qayssar Joudah Fadheel

Department of Pharmacology and Toxicology, College of Pharmacy, University of Babylon, Hillah, Iraq

References

1. Marcianò G., Vocca C., Evangelista M., Palleria C., Muraca L., Galati C., et al. The pharmacological treatment of chronic pain: from guidelines to daily clinical practice. Pharmaceutics 15(4), 1165, 2023. DOI: 10.3390/pharmaceutics15041165

2. Tsegaye D., Yazew A., Gedfew M., Yilak G., Yalew Z.M. Non-pharmacological pain management practice and associated factors among nurses working at comprehensive specialized hospitals. SAGE Open Nurs. 9, 23779608231158979, 2023. DOI: 10.1177/23779608231158979

3. Tohol W.J., Abuejheisheh A.J., Fashafsheh I., Amro N. Using of non-pharmacological pain methods, and the perceived barriers, among nurses in critical care unit in Palestine. BMC Nurs. 22(1), 467, 2023. DOI: 10.1186/s12912-023-01635-9

4. Shi Y., Wu W. Multimodal non-invasive non-pharmacological therapies for chronic pain: mechanisms and progress. BMC Med. 21(1), 372, 2023. DOI: 10.1186/s12916-023-03076-2

5. Gonzalez-Hermosillo D.C., Gonzalez-Hermosillo L.M., Villaseñor-Almaraz M., Ballesteros-Herrera D., Moreno-Jimenez S., Corona-Cedillo R., et al. Current concepts of pain pathways: a brief review of anatomy, physiology, and medical imaging. Curr. Med. Imaging. 20, e190523217114, 2024. DOI: 10.2174/1573405620666230519144112

6. Alencar I.G.M., Dantas J.K.D.S., Matias de Araújo S.C., Fernandes T.E.L., de Araújo P.L.O., da Costa A.B., et al. Non-pharmacological therapies for pain management in paediatric intensive care units: a protocol for a scoping review. BMJ Open 14(2), e074952, 2024. DOI: 10.1136/bmjopen-2023-074952

7. van Veen S., Drenth H., Hobbelen H., Finnema E., Teunissen S., de Graaf E. Non-pharmacological interventions feasible in the nursing scope of practice for pain relief in palliative care patients: a systematic review. Palliat. Care Soc. Pract. 18, 26323524231222496, 2024. DOI: 10.1177/26323524231222496

8. Mangat A.K., Oei J.L., Chen K., Quah-Smith I., Schmölzer G.M. A review of non-pharmacological treatments for pain management in newborn infants. Children (Basel) 5(10), 130, 2018. DOI: 10.3390/children5100130

9. Mawaddah M., Siregar E.S. The effect of murrotal Al-Quran therapy on reducing the intensity of labor pain in the first stage active phase. Int. J. Med. Health 3(4), 127–135, 2024. DOI: 10.55606/ijmh.v3i4.4706

10. Mihailov L., Poroch V., Pascu A.M. Aromatherapy – a non-pharmacological approach in pain control. Bull. Transilv. Univ. Braş. 16(2), 69–84, 2023. DOI: 10.31926/but.ms.2023.65.16.2.9

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Published

10-10-2025

How to Cite

[1]
Jawad, R.H. and Fadheel, Q.J. 2025. Non-pharmacological pain management strategies: a mini-review. Pharmakeftiki . 37, 2S (Oct. 2025). DOI:https://doi.org/10.60988/p.v37i2S.281.