Antibacterial activity of phenylboronic acid on pathogenic isolates of Escherichia coli and Staphylococcus aureus
DOI:
https://doi.org/10.60988/p.v37i2S.241Keywords:
phenylboronic acid; E. coli; S. aureus; agar diffusion; antibacterialAbstract
Boron, a bioactive trace element present in humans, plays a critical role in bone formation and maintenance, and exhibits both antibacterial and anti-inflammatory properties. This study investigated the antibacterial activity of boronic acid at varying concentrations in aqueous solution. Phenylboronic acid (PBA) was prepared at concentrations of 3 mg/mL, 6 mg/mL, and 9 mg/mL, and its antibacterial efficacy was assessed using the agar diffusion method against clinically isolated strains of Escherichia coli and Staphylococcus aureus. The results demonstrated a dose-dependent antibacterial effect of PBA on both bacterial species.
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