Antifungal effects of silver nanoparticles produced by Cinnamomum verum bark extract against fungi isolated from toothbrushes

Authors

  • Raghad Ali Sahib
  • Rasha Fadhel Obaid
  • Hiyam Adnan Ali

DOI:

https://doi.org/10.60988/p.v37i2S.234

Keywords:

toothbrush; green synthesis; antifungal activity; silver nanoparticles; Cinnamomum verum

Abstract

The findings revealed that 50 toothbrush samples used by individuals aged 20–50 years were contaminated with fungi. The infection rate was higher among females (40%), and fungal contamination increased when toothbrushes were used for more than three months. The most frequently isolated fungal species were Aspergillus niger (45%) and Penicillium citrinum (18%), while Fusarium oxysporum was the least common (2%). Silver nanoparticles (Ag NPs) were synthesized via a green method using Cinnamomum verum bark extract. The Ag NPs inhibited the growth of A. niger, A. flavus, A. terreus, and P. citrinum by 44.44%, 75.11%, 84.83%, and 98.66%, respectively, at a concentration of 200 µg/mL. Complete fungal inhibition was observed at 500 µg/mL, with statistically significant differences (p<0.05) compared to the untreated control.

Author Biographies

Raghad Ali Sahib

Department of Biology, College of Science, University of Kufa, Kufa, Iraq

Rasha Fadhel Obaid

Department of Pharmacology and Toxicology, College of Pharmacy, University of Babylon, Hillah, Iraq

Hiyam Adnan Ali

Department of Microbiology, Hammurabi College of Medicine, University of Babylon, Hillah, Iraq

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Published

10-10-2025

How to Cite

[1]
Sahib, R.A. et al. 2025. Antifungal effects of silver nanoparticles produced by Cinnamomum verum bark extract against fungi isolated from toothbrushes. Pharmakeftiki . 37, 2S (Oct. 2025). DOI:https://doi.org/10.60988/p.v37i2S.234.