Synthesis, characterization, and antimicrobial activity of copper oxide nanorods

Authors

  • Fattima Al-Zahra Gabar Gassim
  • Ghassan Jasim Mohammed
  • Esraa Rafied Abass
  • Ahed Kamil Rahi
  • Huda Ahmad Yas
  • Zaid Ahmed Kadhim

DOI:

https://doi.org/10.60988/p.v37i2S.197

Keywords:

co-precipitation; X-ray diffraction; crystallinity; sol-gel process; nanomedicine

Abstract

This study focuses on the synthesis and characterization of copper oxide (CuO) nanorods, which have attracted considerable interest due to their diverse applications in catalysis, electronics, and biomedicine. CuO nanorods were synthesized via a co-precipitation method, employing copper sulfate and sodium hydroxide as precursor materials. The synthesis was optimized by maintaining a pH of 12 and by carefully regulating the calcination temperature, yielding nanoparticles with an average crystallite size of 10.538 nm and a rod-like morphology with a diameter of approximately 25 nm. Structural and morphological features of the synthesized nanoparticles were confirmed through X-ray diffraction and field emission scanning electron microscopy. The antibacterial efficacy of CuO nanorods against Staphylococcus aureus was also assessed, revealing pronounced activity attributed to their nanoscale dimensions and positive surface charge, which facilitate interactions with bacterial membranes. Although the synthesized CuO nanorods exhibit strong potential across multiple domains, limitations related to scalability and particle size uniformity must be addressed in future studies. Overall, this study underscores the antimicrobial promise of CuO nanorods and calls for further research in order to improve their applicability.

Author Biographies

Fattima Al-Zahra Gabar Gassim

Department of Pharmaceutics, College of Pharmacy, University of Babylon, Hillah, Iraq

Ghassan Jasim Mohammed

Department of Pharmaceutics, College of Pharmacy, University of Babylon, Hillah, Iraq

Esraa Rafied Abass

Department of Pharmaceutical Chemistry, College of Pharmacy, University of Babylon, Hillah, Iraq

Ahed Kamil Rahi

Department of Pharmaceutical Chemistry, College of Pharmacy, University of Babylon, Hillah, Iraq

Huda Ahmad Yas

Department of Pharmaceutics, College of Pharmacy, University of Babylon, Hillah, Iraq

Zaid Ahmed Kadhim

Department of Pharmaceutics, College of Pharmacy, University of Babylon, Hillah, Iraq

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Published

10-10-2025

How to Cite

[1]
Gabar Gassim, F.A.-Z. et al. 2025. Synthesis, characterization, and antimicrobial activity of copper oxide nanorods. Pharmakeftiki . 37, 2S (Oct. 2025). DOI:https://doi.org/10.60988/p.v37i2S.197.