The antibiotic susceptibility patterns of uropathogens among adults with recurrent urinary tract infection in Mosul, Iraq

Authors

  • Radhwan N. Al-Zidan College of Pharmacy, University of Mosul, Mosul, Iraq
  • Sameer M. Mahmood
  • Zaid M. Younus College of Pharmacy, University of Mosul, Mosul, Iraq

DOI:

https://doi.org/10.60988/p.v36i2.59

Abstract

The emergence of bacteria resistant to antimicrobial treatments can lead to prolonged hospitalization, increased financial costs, and even mortality. One of the most common bacterial infections, both in hospital and community settings, is recurrent urinary tract infections (UTIs). This study aimed to investigate the antibiotic resistance patterns of the most commonly used antibiotics and identify the causative uropathogenic bacteria isolated from the urine of patients suffering from recurrent UTIs. The study recruited 77 patients diagnosed with recurrent UTIs who had not received antibiotic therapy in the last 14 days, and collected urine samples for analysis. Using the disk diffusion method per the Clinical and Laboratory Standards Institute’s guidelines, the study found that Escherichia coli was the most common uropathogens identified in all patients (51.94%), followed by Staphylococcus aureus (20.77%), K. pneumoniae (9.09%), Proteus spp. (7.79%), Enterobacter (6.49%), and P. aeruginosa (3.89%). Alarmingly, all of the isolated bacterial uropathogens were found to be resistant to at least five of the tested antibiotics. The findings of this study have important implications for the treatment of recurrent UTIs, as they provide valuable information on antibiotic resistance patterns and uropathogenic bacteria that can inform the development of more effective antibiotic regimens. This knowledge will empower physicians with the information they need to make informed decisions when treating recurrent UTIs.

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Published

18-06-2024

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Research Articles